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Best cold flu reliefs - September 2025

Last Updated - September 24, 2025

1
Best Choice
20% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Boiron
20% Off

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

Picked by 416 people in the last week

Boiron

$26.99

$33.99
(20% Off)

More Details
Main highlights
- THE BOIRON PROMISE: We believe there’s a better way to feel better. Since 1932, we’ve been dedicated to providing the purest medicines made from earth’s best resources
- SHORTEN YOUR SYMPTOMS: Oscillo has been shown in clinical studies to help reduce both the duration and the severity of flu-like symptoms when taken at the onset.* Non-drowsy, easy-to-take relief
- HSA & FSA eligible: Oscillococcinum is HSA & FSA eligible
- HOMEOPATHIC FLU RELIEF: Oscillococcinum works with your body to help relieve body aches, headache, fever, chills, and fatigue.* Ideal for ages 2 and up, take at the first sign of flu-like symptoms
- HOLISTIC SUPPORT: Looking for homeopathic flu relief for the whole family? Oscillococcinum’s meltaway pellets dissolve easily in the mouth; no water, chewing, or swallowing required
- A BETTER WAY TO FEEL BETTER: Homeopathic medicines use highly diluted botanical, biological, or mineral substances to relieve symptoms. They work with your body without the risk of known drug interactions
$26.99
$33.99 (20% Off)
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Vicks

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Vicks

$19.97

More Details
Main highlights
- WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
- RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
- POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
- NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
$19.97
3
29% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Nature's Way
29% Off

Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

Nature's Way

$13.75

$19.49
(29% Off)

More Details
Main highlights
- Umcka cold + flu care non-drowsy formula with clinically proven Pelargonium sidoides 1X to shorten duration and reduce severity of common cold symptoms and throat, nasal, bronchial irritations, plus Alpha-CF to reduce flu* symptoms
- Nature's Way Cold+Flu Relief provides cold and flu* symptom relief with a multi-action formula for body aches*, congestion, cough, fever*, runny nose*, and sore throat
- Cold + flu* relief made with a proprietary Pelargonium sidoides 1X and Alpha CF.
- Children 6-12 years of age, chew one tablet two times daily. Adults and children 13 years of age and older chew one tablet three times daily
- At Nature’s Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness
$13.75
$19.49 (29% Off)
4
19% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care
19% Off

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Amazon Basic Care

$10.34

$12.77
(19% Off)

More Details
Main highlights
- MAXIMUM STRENGTH: Get day and night cold and flu relief with these max strength coated caplets. Relieve sore throat and other cold and flu symptoms with Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu
- EFFECTIVE: Daytime relieves minor aches and pains, fever, nasal congestion, sinus pressure, cough and chest congestion; Nighttime relieves minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
- COMBINATION PACK: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu comes in a combination pack for around-the-clock maximum strength, multi-symptom relief for your worst cold and flu symptoms
- COATED CAPLETS: Contain pain reliever/fever reducer, cough suppressant, nasal decongestant, antihistamine, expectorant (antihistamine in nighttime only, expectorant in daytime only)
- ACTIVE INGREDIENTS: Amazon Basic Care Vapor Ice Daytime and Nighttime Severe Cold and Flu help to relieve common cold and flu symptoms, day and night; compare to the active ingredients in Vicks DayQuil and NyQuil Severe VapoCOOL
$10.34
$12.77 (19% Off)
5
Best Value
36% Off

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Nature's Way
36% Off

Nature's Way Cold + Flu Relief Syrup*, Umcka, Sore Throat, Cough, Congestion, Fever*, Body Aches*, Phenylephrine Free, Homeopathic, Non-Drowsy, Berry Flavored, 4 Fl Oz (Packaging May Vary)

Nature's Way

$13.68

$21.49
(36% Off)

More Details
Main highlights
- Non-drowsy formula. (0.45% Alcohol)
- Nature's Way Cold + Flu Relief Syrup is a soothing syrup for cold and flu* symptom relief. It shortens the duration and reduces severity of symptoms associated with the common cold and throat/nasal/bronchial irritations, as well as fever*, body aches*, chills*, and runny nose.*
- Made with clinically proven Pelargonium sidoides 1X, which is proven effective in clinical studies, plus Sambucus nigra 3X & Alpha CF to provide multi-symptom relief of colds and flu*.
- For best results, use at first sign of symptoms and continue use for an additional 48 hours after symptoms cease. Adults & children 13 years of age and older take 1 1/2 teaspoons three times daily. Children 6-12 years of age take 1 teaspoon three times daily.
- At Nature’s Way, we believe nature is the ultimate problem solver. For over 50 years, we have looked to the natural world for inspiration. Our quality vitamins and supplements are formulated to help you find your way to wellness.
$13.68
$21.49 (36% Off)

Best cold flu reliefs - September 2025

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Nature's Way Cold + Flu Relief Syrup, Umcka, Sore Throat, Cough, Congestion, Fever, Body Aches*, Phenylephrine Free, Homeopathic, Non-Drowsy, Berry Flavored, 4 Fl Oz (Packaging May Vary)

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Best cold flu reliefs - September 2025

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Nature's Way Cold + Flu Relief Syrup*, Umcka, Sore Throat, Cough, Congestion, Fever*, Body Aches*, Phenylephrine Free, Homeopathic, Non-Drowsy, Berry Flavored, 4 Fl Oz (Packaging May Vary)

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Sambucol Cold and Flu Relief Tablets - Homeopathic Cold Medicine, Remedy for Adults, Black Elderberry for Colds, Zinc Remedy - 30 Count

Zicam Cold Remedy Zinc Medicated Fruit Drops, Assorted Flavors, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

Nature's Way Cold Relief Hot Drink, Umcka, Homeopathic, Clinically Proven Pelargonium Sidoides 1X, for Cough, Congestion, Sore Throat, Stuffy Nose, Day & Night Formula, 12 Packets (Packaging May Vary)

Amazon Basic Care Daytime Cold and Flu Relief Liquid Caps Softgel, Non-Drowsy Cold Medicine, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

Mucinex Rapid Clear Maximum Strength Cold Medicine & Expectorant, Fever, Pain, Headache, & Excess Mucus Relief with Acetaminophen & Guaifenesin, Rapid Release Caplets for Adults, 20 Count

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Nature's Way Cold + Flu Relief FastActives, Umcka, Homeopathic, Fever*, Sore Throat, Cough, Congestion, Phenylephrine Free, Non-Drowsy, Berry Flavored, 10 Packets (Packaging May Vary)

Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

Amazon Basic Care Nighttime Cold and Flu Relief Softgels, 6 Hour Cold Medicine, Relieves Major Flu Symptoms So You Can Rest, 48 Count (Pack of 1)

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Nature's Way Cold + Flu Relief Syrup, Umcka, Sore Throat, Cough, Congestion, Fever, Body Aches*, Phenylephrine Free, Homeopathic, Non-Drowsy, Berry Flavored, 4 Fl Oz (Packaging May Vary)